Ouabain-induced Hypertension
نویسندگان
چکیده
taneous transfemoral technique. Radiology 89:815-824, 1967 5 Ziegler EE: Infectious mononucleosis: Report of a fatal case with autopsy. Arch Path 37: 196-201, 1944 6 Custer RP, Smith EB: The pathology of infectious mononucleosis. Blood 3:830-857, 1948 7 Fish M, Barton HR: Heart involvement in infectious mononucleosis. Arch Int Med 101 :636-644, 1958 8 Hoagland RJ: The clinical manifestations of infectious mononucleosis; a report of 200 cases. Am J Med Sci 240, 21-29, 1960 9 Niederman JC, hfcCollum RW, Henle G, et al: Infectious mononucleosis: clinical manifestations in relation to EB virus antibodies. JAMA 203:205-209, 1968 10 Webster BH: Cardiac complications of infectious mononucleosis. A review of the literah~re and report of five cases. Am J Med Sci 234:62-70, 1957 11 Abelmann WH: hlyocarditis. New Eng J Med 275:832833, 944-945, 1966 12 de la Chapelle CE, Rossmann CE: hlyocarditis. Circulation 10:747-765, 1954 13 Sidd JJ, Kemp HG, Gorlin R: Acute myocardial infarction in a nineteen-year-old student in the absence of coronary obstructive disease. New Eng J hied 282:1306-1307, 1970 14 Likoff W: Myocardial infarction in subjects with normal coronary arteriograms (editorial ) . Am J Cardiol 28:742743, 1971 15 Nizet PM, Robertson L: Normal coronary arteriogram following nlyocardial infarction in a 17-year-old boy. t\m J Cardio128:715-717, 1971 16 Houck GH: Involvement of the heart in infectious mononucleosis (editorial). Am J Med 14:261-264, 1953
منابع مشابه
The 2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro
Dostanic, Iva, Richard J. Paul, John N. Lorenz, Steven Theriault, James W. Van Huysse, and Jerry B. Lingrel. The 2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro. Am J Physiol Heart Circ Physiol 288: H477–H485, 2005. First published September 30, 2004; doi:10.1152/ajpheart.00083.2004.—Although ouabain is known to induce hyperte...
متن کاملEffect of Sodium Valproate on Ouabain-Induced Arrhythmia in Isolated Guinea-Pig Atria
Sodium valproate (SV), an antiepileptic drug has several mechanism of action. It inhibits voltage sensitive Na+ channels and reduces intracellular Na accumulation. These actions are similar to that of both phenytoin and carbamazepine. We have investigated the direct cardiac action of SV and its effects on ouabain-induced arrhythmia in isolated guinea-pig atria. The guinea-pig atrium was dissect...
متن کاملThe alpha2-isoform of Na-K-ATPase mediates ouabain-induced hypertension in mice and increased vascular contractility in vitro.
Although ouabain is known to induce hypertension, the mechanism of how this cardiac glycoside affects blood pressure is uncertain. The present study demonstrates that the alpha2-isoform of the Na-K-ATPase mediates the pressor effects of ouabain in mice. To accomplish this, we analyzed the effect of ouabain on blood pressure in wild-type mice, where the alpha2-isoform is sensitive to ouabain, an...
متن کاملMembrane biochemistry of the ouabain-resistant potassium transport system.
A 6.5-kilobase fragment of genomic DNA from mutant mouse cells under ouabain selection pressure conferred ouabain resistance when transfected into ouabain-sensitive CV1 green monkey fibroblasts. Ouabain resistance was induced in the presence of 10 microM ouabain. Amiloride (500 microM) completely blocked ouabain-insensitive 86Rb+ uptake into these cells. Plasma membranes from these cells demons...
متن کاملHypertensive effects of the iv administration of picomoles of ouabain.
Ouabain, an endogenous digitalis compound, has been detected in nanomolar concentrations in the plasma of several mammals and is associated with the development of hypertension. In addition, plasma ouabain is increased in several hypertension models, and the acute or chronic administration of ouabain increases blood pressure in rodents. These results suggest a possible association between ouaba...
متن کاملDOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.
BACKGROUND We have shown that the ouabain-sensitive α2 Na,K-ATPase is required for adrenocorticotropic hormone (ACTH)-induced hypertension and gestational blood pressure regulation. It is therefore of interest to explore whether this binding site participates in the development of other forms of hypertension, such as deoxycorticosterone acetate (DOCA)-salt using mutant mice with altered sensiti...
متن کامل